This article talks about how lidocaine overdose happens, the signs and symptoms of lidocaine toxicity, and what to do if you think you've received or taken too much lidocaine. For more acute poisoning with a shorter anticipated duration (e.g., local anesthetic systemic toxicity), higher doses may be reasonable for a shorter period (e.g., 500-1,000 ml infused over 30-60 minutes). Local anesthetic systemic toxicity (LAST) is a rare complication that can develop within minutes of receiving local anesthetics. It’s a medical emergency that causes nervous system and heart issues. This topic will discuss the pathologic pharmacology, mechanisms, and clinical presentation of toxicity, predisposing factors, and prevention and management of LAST. Local Anaesthetic Toxicity- sodium channel blockade - arrhythmias and neurotoxicity Gain essential insights into lidocaine toxicity. Understand this adverse reaction, how it manifests, and effective strategies for safety. Lidocaine is a local anesthetic and generally safe. However, it is possible to develop direct nerve and systemic toxicity with too much lidocaine.